High Impact Chronic Pain (HICP) is defined as the presence of pain on at least half of days in the previous 3-6 months with substantial restriction of functional participation in work, social, and self-care activities. HICP is assessed with several questions assessing the duration, frequency, and impact of chronic pain, as well as one question regarding the impact of pain on work. In the PMC3, those who report pain on most days for the past 3 months, and who report that pain limits their life or work activities, are considered to have HICP.

We compared operational definitions (ICD9/10) that targeted a non-VA research setting (PROUD), a VA research setting (Seal et al., 2019) and non-research quality measurement system, the Healthcare Effectiveness Data and Information Set (HEDIS) and determined that there was overlap across SUD sub-categories of opioid use disorder, alcohol use disorder, other substance used disorders. Based on this review, Primary Care Opioid Use Disorders Treatment Trial (PROUD) was recommended as the phenotype for the PMC-3.

This manuscript described the primary outcomes from a CBT-based intervention designed to address headache attributable to mild TBI and comorbid PTSD in Veterans. We found that the CBT headache intervention produced headache outcomes that were superior to medical management in VA polytrauma and PTSD outcomes comparable to Cognitive Processing Therapy.

The third paper in the three-part series on addressing racism in pain research, the authors advocate for a shared commitment toward an antiracism framework in pain research. They identify community partnerships, diversification of research environments, and changes to dissemination practices.

This second paper in a 3-part series on antiracism in pain research across the translational spectrum focuses on study design factors.

Part one of these three-part series on addressing racism in pain research offers historical and theoretical background, as well as proposed shifts in language and practices in pain research frameworks, to promote the incorporation of antiracism research practices.

Veterans and Caregivers are invited to submit abstracts for poster presentations that highlight research projects, Veteran Engagement Groups (VEGs), or other research-related activities. Posters sessions provide an opportunity meet researchers, other Veterans, and Caregivers from all over the United States. Accepted posters will be displayed during a poster session.

The NSCAP assesses the frequency, targeted outcome (e.g., “to manage pain”), perceived effectiveness, and setting of these approaches.

An early challenge was to ensure that PMC researchers across the 11 national, large-scale pain trials did not co-enroll participants in multiple, concurrent pain trials. Learn about the strategies developed to address this challenge.

In Learn as You Go (LAGO) study designs, the components of the complex package are repeatedly optimized in pre-planned stages, until the intervention package is optimized. In this manuscript, the authors explore the key features of the LAGO’ design, illustrated by the null BetterBirth study, a large-scale public health intervention trial. (DRAFT)