Research Publications

Journals and other articles from partners, and other sources external to the collaboratory.

Recently, a multidisciplinary group of leading experts in pain updated the definition of “pain” on behalf of the International Association for the Study of Pain (IASP). Particularly relevant is the acknowledgement that pain is a personal, subjective and multidimensional experience that can be shaped by a range of biological, psychological and social factors.

In this working document, the Pain Management Collaboratory Biostatistics/Design Workgroup offers an overview of the intraclass correlation coefficient (ICC) and recommendations for researchers planning cluster randomized trials with pain outcomes.

PMC’s Biostatistics/Design Work Group addresses the problem of missing data in pragmatic clinical trials, and offers a survey of methods that some of PMC’s trials are incorporating to prevent missing data.

Researchers, including PMC PI Stephanie Taylor, PhD, MPH, conducted the first study of cost effectiveness of complementary and integrative health (CIH) therapy use among younger Veterans with musculoskeletal pain.

An overview of considerations for covariate-related methodological, statistical and analytical issues, and some additional considerations to studying pain management options…

The SPACE Randomized Clinical Trial, led by Erin Krebs, MD, MS, showed that opioids do not result in better pain-related function or reduced pain intensity when compared to non-opioids. (VA photo by April Eilers)

More than two dozen Yale professors, doctors, and students have published a series of groundbreaking articles on the opioid crisis in the Journal of Law, Medicine and Ethics.

Participants in the SOTA conference identified nine non-pharmacological therapies with sufficient evidence to be implemented across the VHA system as part of pain care.

Treatments such as mindfulness meditation, biofeedback, and hypnosis, among others, have been determined to have at least promising evidence of effectiveness for pain management. (Photo: Joseph Eddins)

For some nonpharmacological approaches for chronic pain management there is emerging evidence of their effectiveness in relatively large scale trials. (photo: Sgt Justin Boling)