Pragmatic Clinical Trials (PCT)

These PCTs on non- pharmacological approaches for pain management and comorbid conditions in settings serving military personnel, veterans and their families were selected based on the (1) importance of the scientific questions and (2) potential to address impediments to research with health care delivery organizations. Demonstration Projects will utilize a phased award UG3/UH3 mechanism, with a planning (UG3) and an implementation (UH3) phase. All projects will be milestone-driven, and moving to the implementation phase (UH3) will be dependent upon the successful progress made during the planning phase (UG3).

Active Projects

Click on the project title(s) below to learn more.

TitlePrincipal Investigator(s)Sponsoring Institution(s)Phase
Cooperative Pain Education and Self management: Expanding Treatment for Real-world Access (Copes ExTRA)Alicia Heapy, PhDVA Connecticut & Yale School of MedicineUG3
Engaging Veterans Seeking Service Connection Payments in Pain TreatmentMarc Rosen, PhD & Steve Martino, PhDVA Connecticut & Yale School of MedicineUG3
Chiropractic Care for Veterans, A Pragmatic Randomized Trial Addressing Dose Effects for cLBPChristine Goertz, DC, PhDPalmer Center for Chiropractic ResearchUG3
Improving Veteran Access to Integrated Management of Low Back PainSteven George, PhD & Nicole Hastings, MD, MHSDurham VA & Duke UniversityUG3
SMART Stepped Care Management for Low Back Pain in Military Health SystemsJulie Fritz, PhD & Dan Rhon, PhDUniversity of Utah & Brooke Army Medical CenterUG3
Whole Health Team vs. Primary Care Group Education to Promote Non-Pharmacological Strategies to Improve Pain, Functioning, and Quality of Life in VeteransKaren Seal, MD & William Becker, MDPalo Alto & VA ConnecticutUG3
Complementary and Integrative Health for Pain in the VA: A National Demonstration ProjectStephanie Taylor, PhD & Steven Zeliadt, PhDVA Greater Los Angeles and VA Puget SoundUG3
Testing Two, Scalable, Veteran-Centric Mindfulness Based Interventions for Chronic Musculoskeletal Pain: A Pragmatics Multisite TrialDiana Burgess, PhDMinneapolis VAUG3
Targeting Chronic Pain in Primary Care Settings Using Internal Behavioral Health ConsultantsJeffrey L. Goodie, PhD & Donald D. McGeary, PhDUniformed Services University & University of Texas Health Science CenterUG3
Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation:A Non -Pharmacologic Alternative for the Treatment of Postoperative painBrian M. Ilfeld, MD,University of California, San DiegoUG3
Resolving the Burden of Low Back Pain in Military Service Members and Veterans: A Multi-Site Pragmatic Clinical Trial (RESOLVE Trial)Shawn Farrokhi, PhDDoD-VA Extremity Trauma and Amputation Center of Excellence (EACE)UG3