Time: 12:00 AM to 1:00 PM ET Series: QUERI Implementation Research Group Speaker: Nazanin Bahraini, PhD Description: This presentation will provide an overview of adaptive research designs and their use in implementation science. Adaptive designs have a lot of power and are intended to boost evidence-based uptake by increasing efficiency (lowering time and cost), while …
adaptive design
What are ways that investigators can plan for study design changes as data accumulates? The authors present Learn-As-you-GO (LAGO) for an adaptive method to apply in stages during a study, and compare against other adaptive designs for trials such as Sequential Multiple Assignment Randomized Trial (SMART) design and Multiphase Optimization Strategy (MOST). Methods are illustrated through the Better Birth Study.
