Research can help find the optimal pathway to limit the negative impacts of pain.
Research & Researchers
Pain is often a complex problem in that everyone experiences it differently. In western medicine, we have very little pragmatic, clinical research on options for managing it effectively, nonpharmacological or otherwise. Additionally, the opioid epidemic has shown that pharmacological approaches may have only minimal benefit for the management of pain and the risk of substantial harms.
In this working document, the Pain Management Collaboratory Biostatistics/Design Workgroup offers an overview of the intraclass correlation coefficient (ICC) and recommendations for researchers planning cluster randomized trials with pain outcomes.
Prevention of Missing Data in Pragmatic Clinical Trials of Nonpharmacologic Interventions for Pain Management
PMC’s Biostatistics/Design Work Group addresses the problem of missing data in pragmatic clinical trials, and offers a survey of methods that some of PMC’s trials are incorporating to prevent missing data.
As the COVID-19 pandemic hit, the PMC adapted its research as needed to continue its progress in advancing research on nonpharmacological pain management during this unprecedented disruption in research, healthcare, and everyday routines that affect how people live with pain.
The issue includes articles related to addressing and assessing risk factors for chronic pain and opioid misuse and articles related to psychological and integrated treatment approaches to pain management and opioid-risk mitigation.
Recently, a multidisciplinary group of leading experts in pain updated the definition of “pain” on behalf of the International Association for the Study of Pain (IASP). Particularly relevant is the acknowledgement that pain is a personal, subjective and multidimensional experience that can be shaped by a range of biological, psychological and social factors.
The Use of Complementary and Integrative Health Approaches for Chronic Musculoskeletal Pain in Younger US Veterans: An Economic Evaluation
Researchers, including PMC PI Stephanie Taylor, PhD, MPH, conducted the first study of cost effectiveness of complementary and integrative health (CIH) therapy use among younger Veterans with musculoskeletal pain.
More than two dozen Yale professors, doctors, and students have published a series of groundbreaking articles on the opioid crisis in the Journal of Law, Medicine and Ethics.