Publications of Interest

Intraclass Correlation Coefficients for Cluster Randomized Trials with Pain Outcomes
In this working document, the Pain Management Collaboratory Biostatistics/Design Workgroup offers an overview of the intraclass correlation coefficient (ICC) and recommendations for researchers planning cluster randomized trials with pain outcomes.

Prevention of Missing Data in Pragmatic Clinical Trials of Nonpharmacologic Interventions for Pain Management
PMC’s Biostatistics/Design Work Group addresses the problem of missing data in pragmatic clinical trials, and offers a survey of methods that some of PMC’s trials are incorporating to prevent missing data.

The Use of Complementary and Integrative Health Approaches for Chronic Musculoskeletal Pain in Younger US Veterans: An Economic Evaluation
Researchers, including PMC PI Stephanie Taylor, PhD, MPH, conducted the first study of cost effectiveness of complementary and integrative health (CIH) therapy use among younger Veterans with musculoskeletal pain.

Covariate Adjustment in Pragmatic Randomized Clinical Trials in Pain Research
An overview of considerations for covariate-related methodological, statistical and analytical issues, and some additional considerations to studying pain management options…

Non-Opioid Drugs and Pain-Related Function
The SPACE Randomized Clinical Trial, led by Erin Krebs, MD, MS, showed that opioids do not result in better pain-related function or reduced pain intensity when compared to non-opioids. (VA photo by April Eilers)

Yale Scholars Tackle Opioid Crisis in Groundbreaking Journal Issue
More than two dozen Yale professors, doctors, and students have published a series of groundbreaking articles on the opioid crisis in the Journal of Law, Medicine and Ethics.